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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">izvestiiatimacad</journal-id><journal-title-group><journal-title xml:lang="ru">Известия Тимирязевской сельскохозяйственной академии</journal-title><trans-title-group xml:lang="en"><trans-title>IZVESTIYA OF TIMIRYAZEV AGRICULTURAL ACADEMY</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0021-342X</issn><publisher><publisher-name>ФГБОУ ВО РГАУ-МСХА имени К.А. Тимирязева</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26897/0021-342X-2024-6-171-180</article-id><article-id custom-type="elpub" pub-id-type="custom">izvestiiatimacad-842</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЗООТЕХНИЯ, БИОЛОГИЯ И ВЕТЕРИНАРНАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LIVESTOCK BREEDING, BIOLOGY AND VETERINARY MEDICINE</subject></subj-group></article-categories><title-group><article-title>Генетическое маркирование живой массы овец мясного  направления продуктивности в раннем возрасте</article-title><trans-title-group xml:lang="en"><trans-title>Genetic marking of live weight of meat sheep at an early age</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9501-8080</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Селионова</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Selionova</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Селионова Марина Ивановна, д-р биол. наук, профессор, заведующий кафедрой разведения, генетики и биотехнологии животных</p><p>127559, г. Москва, ул. Тимирязевская, 49</p></bio><bio xml:lang="en"><p>Marina I. Selionova, DSc (Bio), Professor, Head of the Department of Animal Breeding, Genetics and Biotechnology</p><p>49 Timiryazevskaya St., Moscow, 127550</p></bio><email xlink:type="simple">selionova@rgau-msha.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юлдашбаев</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yuldashbaev</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юлдашбаев Юсупжан Артыкович, д-р с.-х. наук, профессор, академик РАН, профессор кафедры частной зоотехнии</p><p>127559, г. Москва, ул. Тимирязевская, 49</p></bio><bio xml:lang="en"><p>Yusupzhan A. Yuldashbaev,  DSc (Ag), Professor, Full  Member of the Russian Academy of Sciences, Professor at the Department of Specific Animal Science</p><p>49 Timiryazevskaya St., Moscow, 127550</p></bio><email xlink:type="simple">selionova@rgau-msha.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гладких</surname><given-names>М. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Gladkikh</surname><given-names>M. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гладких Марианна Юрьевна, канд. с.-х. наук, доцент кафедры разведения, генетики и биотехнологии животных</p><p>127559, г. Москва, ул. Тимирязевская, 49</p></bio><bio xml:lang="en"><p>Marianna Yu. Gladkikh, CSc (Ag), Associate Professor at the Department of Animal Breeding, Genetics and Biotechnology</p><p>49 Timiryazevskaya St., Moscow, 127550</p></bio><email xlink:type="simple">Marianna.gladkikh@rgau-msha.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чылбак-оол</surname><given-names>С. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Chylbak-ool</surname><given-names>S. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Салбак Олеговна Чылбак-оол, канд. биол. наук, доцент кафедры разведения, генетики и биотехнологии животных</p><p>127559, г. Москва, ул. Тимирязевская, 49</p></bio><bio xml:lang="en"><p>Salbak O. Chylbak-ool, CSc (Bio), Associate Professor at the Department of Animal Breeding, Genetics and Biotechnology</p><p>49 Timiryazevskaya St., Moscow, 127550</p></bio><email xlink:type="simple">shylbakool@rgau-msha.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский государственный аграрный университет – МСХА имени К.А. Тимирязева</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian State Agrarian University – Moscow Timiryazev Agricultural Academy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>09</day><month>12</month><year>2024</year></pub-date><volume>0</volume><issue>6</issue><fpage>171</fpage><lpage>180</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Селионова М.И., Юлдашбаев Ю.А., Гладких М.Ю., Чылбак-оол С.О., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Селионова М.И., Юлдашбаев Ю.А., Гладких М.Ю., Чылбак-оол С.О.</copyright-holder><copyright-holder xml:lang="en">Selionova M.I., Yuldashbaev Y.A., Gladkikh M.Y., Chylbak-ool S.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://izvestiia.timacad.ru/jour/article/view/842">https://izvestiia.timacad.ru/jour/article/view/842</self-uri><abstract><p>В исследованиях проведен анализ генетического разнообразия полиморфизма в генах кальпаина (CAPN1) и лептина (LEP) у разных половозрастных групп калмыцкой курдючной породы и влияния разных генотипов на живую массу и среднесуточный прирост у ярочек и баранчиков. Установлено, что у баранов-производителей в локусе CAPN1 выше доля аллеля С, а среди овцематок аллели Т и С встречались с одинаковой частотой. У ярочек и баранчиков в отличие от родительского поголовья чаще выявлялся аллель Т. В локусе LEP наиболее часто встречались животные с генотипом AG. Для обоих локусов не выявлены отклонения от равновесия Харди-Вайнберга. Живая масса ярочек и баранчиков разных генотипов по гену CAPN1 не различалась при рождении, но к возрасту отбивки как баранчики, так и ярочки с генотипом СС, превосходили молодняк других генотипов. Не выявлены достоверные различия между живой массой и среднесуточным приростом у ярочек и баранчиков разных генотипов по гену LEP, за исключением того, что баранчики генотипа AA характеризовались большей живой массой при рождении, чем их сверстники. Установлено, что бараны-производители с генотипом АА достоверно уступали по живой массе баранам с другими генотипами, в то время как овцематки с генотипом АА, напротив, превосходили овцематок других групп по этому признаку.</p></abstract><trans-abstract xml:lang="en"><p>The study analyzed the genetic diversity of polymorphism in the calpain (CAPN1) and leptin (LEP) genes in ewes and rams of the Kalmyk fat-tailed breed and the influence of different genotypes on their live weight and average daily gain. It was found that the proportion of the C allele in the CAPN1 locus was higher in rams, while the T and C alleles were equally frequent in ewes. The T allele was more common in ewes and rams than in the parent stock. In the LEP locus, animals with the AG genotype were most common. No deviations from the Hardy-Weinberg equilibrium were found for either locus. Ewes and rams of different genotypes for the CAPN1 gene did not differ in live weight at birth, but by the age of weaning, both rams and ewes with the CC genotype outperformed the young animals of other genotypes. No reliable differences were found between the live weight and average daily gain in ewes and rams of different genotypes for the LEP gene, except that the rams of the AA genotype were characterized by a higher live weight at birth than their peers. It was found that stud rams with the AA genotype were significantly inferior in live weight to rams with other genotypes, while ewes with the AA genotype outperformed ewes of other groups in this trait.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>живая масса</kwd><kwd>генотипирование</kwd><kwd>калмыцкая курдючная порода</kwd><kwd>CAPN1</kwd><kwd>LEP</kwd></kwd-group><kwd-group xml:lang="en"><kwd>live weight</kwd><kwd>genotyping</kwd><kwd>Kalmyk fat-tailed breed</kwd><kwd>CAPN1</kwd><kwd>LEP</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Горлов И.Ф., Широкова Н.В., Колосов Ю.А., Беляевская А.В. 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