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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">izvestiiatimacad</journal-id><journal-title-group><journal-title xml:lang="ru">Известия Тимирязевской сельскохозяйственной академии</journal-title><trans-title-group xml:lang="en"><trans-title>IZVESTIYA OF TIMIRYAZEV AGRICULTURAL ACADEMY</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0021-342X</issn><publisher><publisher-name>ФГБОУ ВО РГАУ-МСХА имени К.А. Тимирязева</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26897/0021-342X-2024-6-141-161</article-id><article-id custom-type="elpub" pub-id-type="custom">izvestiiatimacad-690</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЗООТЕХНИЯ, БИОЛОГИЯ И ВЕТЕРИНАРНАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LIVESTOCK BREEDING, BIOLOGY AND VETERINARY MEDICINE</subject></subj-group></article-categories><title-group><article-title>Возрастная динамика многоплодия мини-свиней ИЦиГ СО РАН и ее связь с белой мастью</article-title><trans-title-group xml:lang="en"><trans-title>Age-related prolificacy dynamics in mini-pigs of ICiG SB RAS and its association with the white coat color</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8239-5450</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитин</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitin</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никитин Сергей Вячеславович, канд. биол. наук, старший научный сотрудник лаборатории молекулярной генетики и селекции сельскохозяйственных животных</p><p>630090, г. Новосибирск, пр-кт Академика Лаврентьева, 10</p></bio><bio xml:lang="en"><p>Sergey V. Nikitin, CSc (Bio), Senior Research Associate at the Laboratory of Molecular Genetics and Breeding of Farm Animals</p><p>10 Akademika Lavrentʹeva Ave., Novosibirsk, 630090</p></bio><email xlink:type="simple">nsv1956@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4767-0795</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Князев</surname><given-names>С. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Knyazev</surname><given-names>S. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Князев Сергей Павлович, канд. биол. наук, доцент, доцент кафедры частной зоотехнии и кормления животных</p><p>630039, г. Новосибирск, ул. Добролюбова, 160</p></bio><bio xml:lang="en"><p>Sergey P. Knyazev, CSc (Bio),  Associate  Professor,  Associate  Professor at the Department of Specific Animal Science and Animal Feeding</p><p>160 Dobrolubova St., Novosibirsk, 630039</p></bio><email xlink:type="simple">knyser@rambler.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1337-5093</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Запорожец</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaporozhets</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Запорожец Вера Ивановна, зоотехник лаборатории молекулярной генетики и селекции сельскохозяйственных животных</p><p>630090, г. Новосибирск, пр-кт Академика Лаврентьева, 10</p></bio><bio xml:lang="en"><p>Vera I. Zaporozhets, Zootechnician at the Laboratory of Molecular Genetics and Breeding of Farm Animals</p><p>10 Akademika Lavrentʹeva Ave., Novosibirsk, 630090</p></bio><email xlink:type="simple">verazaporozec9@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коршунова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Korshunova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Коршунова Елена Викторовна, старший лаборант лаборатории молекулярной генетики и селекции сельскохозяйственных животных</p><p>630090, г. Новосибирск, пр-кт Академика Лаврентьева, 10</p></bio><bio xml:lang="en"><p>Elena V. Korshunova, Research Technician at the Laboratory of Molecular Genetics and Breeding of Farm Animals</p><p>10 Akademika Lavrentʹeva Ave., Novosibirsk, 630090</p></bio><email xlink:type="simple">Len.ediger2009@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0885-2772</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шатохин</surname><given-names>К. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shatokhin</surname><given-names>K. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шатохин Кирилл Сергеевич, канд. биол. наук, старший научный сотрудник лаборатории прикладной биоинформатики</p><p>630039, г. Новосибирск, ул. Добролюбова, 160</p></bio><bio xml:lang="en"><p>Kirill S. Shatohin, CSc    (Bio), Senior Research Associate at the Laboratory of Applied Bioinformatics</p><p>160 Dobrolubova St., Novosibirsk, 630039</p></bio><email xlink:type="simple">true_genetic@mai.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ермолаев</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Ermolaev</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ермолаев Виктор Иванович, д-р биол. наук, профессор, профессор кафедры частной зоотехнии и кормления животных</p><p>630039, г. Новосибирск, ул. Добролюбова, 160</p></bio><bio xml:lang="en"><p>Viktor I. Ermolaev, DSc (Bio),  Professor,  Professor  at  the  Department of Specific Animal Science and Animal Feeding</p><p>160 Dobrolubova St., Novosibirsk, 630039</p></bio><email xlink:type="simple">ermolaev@bionet.nsc.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Институт цитологии и генетики Сибирского отделения РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Новосибирский государственный аграрный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Agrarian University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>17</day><month>08</month><year>2024</year></pub-date><volume>0</volume><issue>6</issue><fpage>141</fpage><lpage>161</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Никитин С.В., Князев С.П., Запорожец В.И., Коршунова Е.В., Шатохин К.С., Ермолаев В.И., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Никитин С.В., Князев С.П., Запорожец В.И., Коршунова Е.В., Шатохин К.С., Ермолаев В.И.</copyright-holder><copyright-holder xml:lang="en">Nikitin S.V., Knyazev S.P., Zaporozhets V.I., Korshunova E.V., Shatokhin K.S., Ermolaev V.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://izvestiia.timacad.ru/jour/article/view/690">https://izvestiia.timacad.ru/jour/article/view/690</self-uri><abstract><p>В статье представлены результаты анализа особенностей динамики многоплодия свиноматок (числа новорожденных в помете) в селекционной группе мини-свиней ИЦиГ СО РАН. Показано, что форма динамики возрастных изменений данного признака у мини-свиней существенно отличается от описанной ранее у свиней кемеровской породы. У свиней кемеровской породы она имеет форму параболы, у мини-свиней ИЦиГ СО РАН – это два последовательных прямолинейных отрезка. Сравнение многоплодия белых (генотип I/…) и небелых (генотип i/i) мини-свиней ИЦиГ СО РАН показало статистически значимое превосходство средних значений признака у свиноматок с генотипом I/…, а также различие динамик его возрастных изменений в сравниваемых группах. Разница по величине среднего многоплодия между носителями доминантного аллеля I эпистатической белой масти и гомозиготами по рецессивному «небелому» аллелю i сопоставима с различием по данному признаку между многои среднеплодными породами домашних свиней европейской селекции. Динамики возрастных изменений многоплодия показывают, что высокое значение признака у белых мини-свиней обусловлено большей продолжительностью периода формирования репродуктивного потенциала. У небелых мини-свиней он продолжается с 1-го по 3-й опоросы, у белых – с 1-го по 4-й. Сравнение реципрокных скрещиваний: белая свиноматка + небелый хряк и небелая свиноматка + белый хряк – показало достоверное превышение среднего многоплодия первого из указанных типов скрещиваний над средним многоплодием второго. Полученный результат позволяет предположить, что более высокое многоплодие белых свиноматок мини-свиней ИЦиГ СО РАН обусловлено особенностями их собственного организма, а не связано с пренатальной жизнеспособностью потомков.</p></abstract><trans-abstract xml:lang="en"><p>The article presents the results of the prolificacy dynamics analysis (the number of newborn piglets per litter) in the mini-pig breeding group of ICiG SB RAS. It is shown that the form of agerelated dynamics of this trait in mini-pigs differs significantly from that described earlier in the Kemerovo breed. In the latter it has the shape of a parabola, in the former it has two consecutive rectilinear segments. The comparison of prolificacy of white (genotype I/…) and non-white (genotype i/i) mini-pigs of ICiG SB RAS showed a statistically significant superiority of the average values of the trait in sows with genotype I/…, as well as the difference in the age-related dynamics in the compared groups. The difference in the mean prolificacy between carriers of the dominant allele I of the epistatic white coat color and homozygotes for the recessive ‘non-white’ allele i is comparable to the difference in this trait between multiand medium-fertile breeds of European domestic pigs. The age-related prolificacy dynamics show that the high value of the trait in white mini-pigs is due to the longer period of of reproductive potential development. In nonwhite mini-pigs it lasts from the 1st to the 3rd farrow, in white pigs from the 1st to the 4th farrow.</p><p>A comparison of the reciprocal crosses of white sows with non-white boars and non-white sows with white boars showed that the average prolificacy of the first type of cross was significantly higher than that of the second type. The obtained result suggests that the higher prolificacy of white sows of mini-pigs of ICiG SB RAS is due to the characteristics of their own organism, and is not related to the prenatal viability of the offspring.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>многоплодие</kwd><kwd>мини-свиньи ИЦиГ СО РАН</kwd><kwd>эпистатическая белая масть</kwd><kwd>динамика возрастных изменений признака</kwd><kwd>выравнивание способом взвешенной скользящей средней</kwd></kwd-group><kwd-group xml:lang="en"><kwd>prolificacy</kwd><kwd>mini-pigs of ICiG SB RAS</kwd><kwd>epistatic white coat color</kwd><kwd>age-related dynamics in the trait</kwd><kwd>alignment using a weighted moving average method</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа поддержана бюджетным проектом № FWNR-2022-0023</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Иванчук В. 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